COMPARING POPULATION-LEVEL HUMORAL AND CELLULAR IMMUNITY TO SARS-COV-2 IN BANGALORE, INDIA



Spatiotemporal Patterns of Substance P-Bound MRGPRX2 Reveal a Novel Connection Between Macropinosome Resolution and Secretory Granule Regeneration in Mast Cells

MRGPRX2, the human member of the MAS-related G protein coupled receptors (Mrgprs), serves as the cellular Supplements target of human mast cells (MCs) for innate ligands, including neuropeptides and antimicrobial peptides.In addition, MRGPRX2 also functions as the receptor for multiple FDA-approved drugs.As such, MRGPRX2 is a mediator of MC respons

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Remyelination protects neurons from DLK-mediated neurodegeneration

Abstract Chronic demyelination and oligodendrocyte loss deprive neurons of crucial support.It is the degeneration of neurons and their connections that drives progressive disability in demyelinating disease.However, whether chronic demyelination triggers neurodegeneration and how it may do so remain unclear.We characterize two genetic mouse models

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